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Malignant mesothelioma is an aggressive and fatal neoplasm of serous membranes that still shows a rising incidence worldwide. This book covers all the important aspects of the disease by bringing together contributions from selected experts in the fields of epidemiology, imaging, pathological diagnosis, therapy, genetics, and screening. Special emphasis is placed on the latest diagnostic techniques and current therapy standards. In addition, the mineralogy of asbestos is reviewed and clear advice is included on the analysis of tissue mineral fiber content. By providing a compact, scientifically based, and up-to-date overview of the management of malignant mesothelioma, this volume will be invaluable for all clinicians and pathologists who are engaged in the diagnosis and treatment of the disease or in related research.

This volume is the most up-to-date text available on diffuse malignant mesothelioma and includes all the newest imaging modalities, immunohistochemical features, and ever-expanding information on the molecular characteristics of the cancer. In-depth chapters contain fully referenced text as well as detailed tables and images. While the primary audiences for this book are pathologists and pathology residents, the broad examination of diffuse malignant mesothelioma, including its epidemiology, makes this book valuable to radiologists, surgeons, oncologists, and other clinical physicians and their residents as well. Written by experts in the field, Diffuse Malignant Mesothelioma is a concise yet comprehensive resource for clinicians involved in the management of one of the most widely recognized and feared cancers in the world.

A long, long time ago in Ancient Egypt ...An unpleasant prophecy by the ancient gods seriously scares the Pharaoh. He orders all his confidants to his court. Thethriving meadows, once reclaimed from the desert, are now threatened by desiccation. Worse than that, future harvests are going to be annihilated!As one of the confidants of the Pharaoh, now is the time to show your skills. You are accompanied by some more or less motivated consultants and architects who will do everything possible to stand by your side during your mission.The Pharaoh commands you into an inhospitable desert. It is your mission to explore the land, to find oases and open up barren land.Colonize unused lands and protect the whole empire from a devastating famine!Commandthe lively Egyptians in an extensive campaign,which is composed of many differentchallenges. It will be necessary to create thriving metropolises, transform deserts into fertile land,upgrade branches of production andprotect your settlementagainst natural disasters or unpleasant contemporaries.Trade resources at your market, search for treasuries, build bridges togain access toremote places and provide your population with food as well as in good mood. By establishing a well-developed economy, your main goal is toprovide resources to the Pharaohs warehouses, sothe threat of a famine can be prevented!An exciting and entertaining mixture of time-management and strategyalong with many teeming characters is waiting for you.Features:

Build an empire out of its grass hut roots! Take the role of a 300-year old emperor cursed to live without his true love until he appeases his god for a grievous offense. Gather resources, research new tools and build bigger and better accommodations as you care for your people and attract new citizens to your fold.  Featuring outstanding graphics and a breathtaking score, Settlement: Colossus is as epic as it is thrilling!

The kingdoms treasury is nothing but a gaping hole of emptiness. The liege lord is utterly discontented and astonished – what could be the best way to fill up the treasury again?The king appoints you to liege man in “Royal Settlement 1450“. Your task is to build towns, villages and trade-routes in order to turn wild nature into prosperous and primarily profitable terrain.There is no time to lean back because the king is waiting for profit. Patience has never been one of his strengths! But your chances of success are high. Don’t forget to regulary pay moderate tribute to keep the king well-disposed.If you fail to succeed in time and fall behind with paying tribute, you will lose the king’s benevolence…The game is an exciting and entertaining mixture between time-management and real-time strategy!Features: